BONNIE BASSLER | Ann E. Cutting | Princeton University | National Academy of Sciences
Genius At Work
by
Tracy Staton
Welcome to one of the world's most prestigious
microbiology labs. It's one part theater, one part brilliance - all
overseen by an aerobics-teaching diva who loves
bacteria.
. PHOTOGRAPHS BY SEAN McCORMICK. PHOTO
ILLUSTRATION BY ANN E. CUTTING.
BONNIE BASSLER CARRIES A FLASK INTO A SMALL,
WINDOWLESS ROOM AND CLOSES THE DOOR BEHIND HER. SHE TURNS OFF
THE LIGHT. A FLUORESCENT BLUE-GREEN GLOW EMANATES FROM THE FLASK,
HIGHLIGHTING HER HANDS, TINGING HER SKIN. INDUSTRIAL CHEMICAL?
RADIOACTIVE ISOTOPE? THE WARM, MUSTY ODOR IN THE ROOM SAYS NO -
ONLY SOMETHING LIVING COULD SMELL LIKE DECOMPOSING GUPPY FOOD. AND
IN A WAY, THAT'S WHAT THIS IS:
IT'S AN OCEANGOING BACTERIA CALLED
VIBRIO HARVEYI, WHICH LIGHTS UP WHEN
IT'S PRESENT IN NUMBERS.
V. harveyi is the bacterium that launched
Bassler into a field of microbiology known as quorum sensing -
named for bacteria's ability to alert one another when a critical
mass of their brethren is nearby - with her own eponymous lab at
Princeton University. It's the bacterium that ushered her into the
select group of MacArthur Fellows and into the National Academy of
Sciences. It's the bacterium that taught Bassler its language.
You could say that Bassler loves
V.
harveyi. She even loves its funky scent, which works its way
into the throat and sinuses, where it lingers. Standing in the dark
lab, holding up the luminescent flask, her face lit by her glowing
offspring, she might be a parody of a Fra Angelico
Madonna and Child.
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